Alert for Men: Vitamin D Deficiency Increases Risk of Aggressive Prostate Cancer
July 24, 2014
Researchers at Northwestern University and the University of Illinois have found that men at high risk for prostate cancer stand a bigger chance of being diagnosed with more aggressive and advanced forms of the disease if they are deficient in vitamin D.
A deficiency could be an indicator of “advanced prostate tumor progression in large segments of the general population,” according to Adam Murphy, M.D., a Northwestern urologist and the lead researcher.
The findings emerged from a study of 667 European American and African American men, ages 40-79, who underwent initial prostate biopsies. Until this investigation, the association between vitamin D status and prostate biopsy outcomes in men with elevated PSA (prostate-specific antigen) levels had not been evaluated.
In the study, deficiencies of vitamin D were linked to a 3.5 times increased risk of an aggressive tumor and about a 2.5 times increased risk for an advanced tumor among European Americans. For African Americans, the increased risk was nearly 5 times and 4.2 times, respectively.
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